Safety of hydroxychloroquine in healthcare workers for COVID-19 prophylaxis.
Identifieur interne : 000017 ( Main/Exploration ); précédent : 000016; suivant : 000018Safety of hydroxychloroquine in healthcare workers for COVID-19 prophylaxis.
Auteurs : Atiya R. Faruqui [Inde] ; Denis Xavier [Inde] ; Sandhya K. Kamat [Inde] ; Sujith J. Chandy [Inde] ; Bikash Medhi [Inde] ; Raakhi K. Tripathi [Inde] ; Yashashri C. Shetty [Inde] ; John Michael Raj [Inde] ; Sandeep Kaushal [Inde] ; S. Balakrishnan [Inde] ; Shubham Atal [Inde] ; Santanu K. Tripathi [Inde] ; Dinesh K. Badyal [Inde] ; Harihar Dikshit [Inde] ; Sukalyan Saha Roy [Inde] ; Niyati Trivedi [Inde] ; Suparna Chatterjee [Inde] ; Chetna Desai [Inde] ; C D Tripathi [Inde] ; Nirmala N. Rege [Inde] ; Pooja Gupta [Inde] ; R. Raveendran [Inde] ; Rajni Kaul [Inde] ; Nilima A. Kshirsagar [Inde]Source :
- The Indian journal of medical research [ 0971-5916 ]
Descripteurs français
- KwdFr :
- MESH :
- effets indésirables : Hydroxychloroquine.
- usage thérapeutique : Hydroxychloroquine.
- Femelle, Humains, Mâle, Personnel de santé, Prophylaxie pré-exposition, Études transversales.
English descriptors
- KwdEn :
- MESH :
- chemical , adverse effects : Hydroxychloroquine.
- drug therapy : COVID-19.
- prevention & control : COVID-19.
- chemical , therapeutic use : Hydroxychloroquine.
- Cross-Sectional Studies, Female, Health Personnel, Humans, Male, Pre-Exposure Prophylaxis.
Abstract
Background & objectives
Hydroxychloroquine (HCQ), reported to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication in in vitro studies, has been recommended for prophylaxis of COVID-19 in healthcare workers (HCWs). The objective of this study was to assess short-term adverse events (AEs) of HCQ in HCWs.
Methods
This cross-sectional study among consenting HCWs taking prophylaxis and working in hospitals with COVID-19 patients used online forms to collect details of HCWs, comorbidities, prophylactic drugs used and AEs after the first dose of HCQ. Verification of dose and AEs was done by personal contact. Multivariate logistic regression analysis was done to determine the effect of age, gender and dose of HCQ on AE.
Results
Of the 1303 HCWs included, 98.4 per cent (n=1282) took HCQ and 66 per cent (n=861) took 800 mg as first day's dose. Among the 19.9 per cent (n=259) reporting AEs, 1.5 per cent (n=20) took treatment for AE, none were hospitalized and three discontinued HCQ. Gastrointestinal AEs were the most common (172, 13.2%), with less in older [odds ratio (OR) 0.56, 95% confidence interval (CI) 0.35-0.89], with more in females (OR 2.46, 95% CI 1.78-3.38) and in those taking a total dose of 800 mg on day one compared to a lower dose. Hypoglycaemia (1.1%, n=14), cardiovascular events (0.7%, n=9) and other AEs were minimal.
Interpretation & conclusions
HCQ prophylaxis first dose was well tolerated among HCWs as evidenced by a low discontinuation. For adverse effects, a small number required treatment, and none required hospitalization. The study had limitations of convenience sampling and lack of laboratory and electrocardiography confirmation of AEs.
DOI: 10.4103/ijmr.IJMR_2294_20
PubMed: 33818480
Affiliations:
Links toward previous steps (curation, corpus...)
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Faruqui</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, St. John's Medical College, Bengaluru, Karnataka, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology, St. John's Medical College, Bengaluru, Karnataka</wicri:regionArea><wicri:noRegion>Karnataka</wicri:noRegion></affiliation></author><author><name sortKey="Xavier, Denis" sort="Xavier, Denis" uniqKey="Xavier D" first="Denis" last="Xavier">Denis Xavier</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, St. John's Medical College, Bengaluru, Karnataka, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology, St. John's Medical College, Bengaluru, Karnataka</wicri:regionArea><wicri:noRegion>Karnataka</wicri:noRegion></affiliation></author><author><name sortKey="Kamat, Sandhya K" sort="Kamat, Sandhya K" uniqKey="Kamat S" first="Sandhya K" last="Kamat">Sandhya K. 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Shetty</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology & Therapeutics, Seth Gordhandas Sunderdas Medical College & King Edwards Medical Hospital, Mumbai, Maharashtra, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology & Therapeutics, Seth Gordhandas Sunderdas Medical College & King Edwards Medical Hospital, Mumbai, Maharashtra</wicri:regionArea><wicri:noRegion>Maharashtra</wicri:noRegion></affiliation></author><author><name sortKey="Raj, John Michael" sort="Raj, John Michael" uniqKey="Raj J" first="John Michael" last="Raj">John Michael Raj</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biostatistics, St. John's Medical College, Bengaluru, Karnataka, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Biostatistics, St. John's Medical College, Bengaluru, Karnataka</wicri:regionArea><wicri:noRegion>Karnataka</wicri:noRegion></affiliation></author><author><name sortKey="Kaushal, Sandeep" sort="Kaushal, Sandeep" uniqKey="Kaushal S" first="Sandeep" last="Kaushal">Sandeep Kaushal</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, Dayanand Medical College & Hospital, Ludhiana, Punjab, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology, Dayanand Medical College & Hospital, Ludhiana, Punjab</wicri:regionArea><wicri:noRegion>Punjab</wicri:noRegion></affiliation></author><author><name sortKey="Balakrishnan, S" sort="Balakrishnan, S" uniqKey="Balakrishnan S" first="S" last="Balakrishnan">S. Balakrishnan</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh</wicri:regionArea><wicri:noRegion>Madhya Pradesh</wicri:noRegion></affiliation></author><author><name sortKey="Atal, Shubham" sort="Atal, Shubham" uniqKey="Atal S" first="Shubham" last="Atal">Shubham Atal</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh</wicri:regionArea><wicri:noRegion>Madhya Pradesh</wicri:noRegion></affiliation></author><author><name sortKey="Tripathi, Santanu K" sort="Tripathi, Santanu K" uniqKey="Tripathi S" first="Santanu K" last="Tripathi">Santanu K. 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Badyal</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, Christian Medical College, Ludhiana, Punjab, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology, Christian Medical College, Ludhiana, Punjab</wicri:regionArea><wicri:noRegion>Punjab</wicri:noRegion></affiliation></author><author><name sortKey="Dikshit, Harihar" sort="Dikshit, Harihar" uniqKey="Dikshit H" first="Harihar" last="Dikshit">Harihar Dikshit</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, Indira Gandhi Institute of Medical Science, Patna, Bihar, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology, Indira Gandhi Institute of Medical Science, Patna, Bihar</wicri:regionArea><wicri:noRegion>Bihar</wicri:noRegion></affiliation></author><author><name sortKey="Roy, Sukalyan Saha" sort="Roy, Sukalyan Saha" uniqKey="Roy S" first="Sukalyan Saha" last="Roy">Sukalyan Saha Roy</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, Indira Gandhi Institute of Medical Science, Patna, Bihar, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology, Indira Gandhi Institute of Medical Science, Patna, Bihar</wicri:regionArea><wicri:noRegion>Bihar</wicri:noRegion></affiliation></author><author><name sortKey="Trivedi, Niyati" sort="Trivedi, Niyati" uniqKey="Trivedi N" first="Niyati" last="Trivedi">Niyati Trivedi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, Medical College Baroda, Vadodara, Ahmedabad, Gujarat, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology, Medical College Baroda, Vadodara, Ahmedabad, Gujarat</wicri:regionArea><wicri:noRegion>Gujarat</wicri:noRegion></affiliation></author><author><name sortKey="Chatterjee, Suparna" sort="Chatterjee, Suparna" uniqKey="Chatterjee S" first="Suparna" last="Chatterjee">Suparna Chatterjee</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, Institute of Postgraduate Medical Education & Research, Kolkata, West Bengal, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology, Institute of Postgraduate Medical Education & Research, Kolkata, West Bengal</wicri:regionArea><wicri:noRegion>West Bengal</wicri:noRegion></affiliation></author><author><name sortKey="Desai, Chetna" sort="Desai, Chetna" uniqKey="Desai C" first="Chetna" last="Desai">Chetna Desai</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, B.J. Medical College, Ahmedabad, Gujarat, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology, B.J. Medical College, Ahmedabad, Gujarat</wicri:regionArea><wicri:noRegion>Gujarat</wicri:noRegion></affiliation></author><author><name sortKey="Tripathi, C D" sort="Tripathi, C D" uniqKey="Tripathi C" first="C D" last="Tripathi">C D Tripathi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, Vardhman Mahavir Medical College & Safdarjung Hospital, New Delhi, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology, Vardhman Mahavir Medical College & Safdarjung Hospital, New Delhi</wicri:regionArea><wicri:noRegion>New Delhi</wicri:noRegion></affiliation></author><author><name sortKey="Rege, Nirmala N" sort="Rege, Nirmala N" uniqKey="Rege N" first="Nirmala N" last="Rege">Nirmala N. Rege</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology & Therapeutics, Seth Gordhandas Sunderdas Medical College & King Edwards Medical Hospital, Mumbai, Maharashtra, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology & Therapeutics, Seth Gordhandas Sunderdas Medical College & King Edwards Medical Hospital, Mumbai, Maharashtra</wicri:regionArea><wicri:noRegion>Maharashtra</wicri:noRegion></affiliation></author><author><name sortKey="Gupta, Pooja" sort="Gupta, Pooja" uniqKey="Gupta P" first="Pooja" last="Gupta">Pooja Gupta</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, All India Institute of Medical Sciences, New Delhi, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology, All India Institute of Medical Sciences, New Delhi</wicri:regionArea><wicri:noRegion>New Delhi</wicri:noRegion></affiliation></author><author><name sortKey="Raveendran, R" sort="Raveendran, R" uniqKey="Raveendran R" first="R" last="Raveendran">R. Raveendran</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, Jawaharlal Institute of Postgraduate Education & Research, Puducherry, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology, Jawaharlal Institute of Postgraduate Education & Research, Puducherry</wicri:regionArea><wicri:noRegion>Puducherry</wicri:noRegion></affiliation></author><author><name sortKey="Kaul, Rajni" sort="Kaul, Rajni" uniqKey="Kaul R" first="Rajni" last="Kaul">Rajni Kaul</name><affiliation wicri:level="1"><nlm:affiliation>Division of Basic Medical Sciences, New Delhi, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Division of Basic Medical Sciences, New Delhi</wicri:regionArea><wicri:noRegion>New Delhi</wicri:noRegion></affiliation></author><author><name sortKey="Kshirsagar, Nilima A" sort="Kshirsagar, Nilima A" uniqKey="Kshirsagar N" first="Nilima A" last="Kshirsagar">Nilima A. Kshirsagar</name><affiliation wicri:level="1"><nlm:affiliation>National Chair Clinical Pharmacology, Indian Council for Medical Research, New Delhi, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>National Chair Clinical Pharmacology, Indian Council for Medical Research, New Delhi</wicri:regionArea><wicri:noRegion>New Delhi</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2021">2021 Jan & Feb</date><idno type="RBID">pubmed:33818480</idno><idno type="pmid">33818480</idno><idno type="doi">10.4103/ijmr.IJMR_2294_20</idno><idno type="wicri:Area/Main/Corpus">000136</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000136</idno><idno type="wicri:Area/Main/Curation">000136</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000136</idno><idno type="wicri:Area/Main/Exploration">000136</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Safety of hydroxychloroquine in healthcare workers for COVID-19 prophylaxis.</title><author><name sortKey="Faruqui, Atiya R" sort="Faruqui, Atiya R" uniqKey="Faruqui A" first="Atiya R" last="Faruqui">Atiya R. Faruqui</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, St. John's Medical College, Bengaluru, Karnataka, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology, St. John's Medical College, Bengaluru, Karnataka</wicri:regionArea><wicri:noRegion>Karnataka</wicri:noRegion></affiliation></author><author><name sortKey="Xavier, Denis" sort="Xavier, Denis" uniqKey="Xavier D" first="Denis" last="Xavier">Denis Xavier</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, St. John's Medical College, Bengaluru, Karnataka, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology, St. John's Medical College, Bengaluru, Karnataka</wicri:regionArea><wicri:noRegion>Karnataka</wicri:noRegion></affiliation></author><author><name sortKey="Kamat, Sandhya K" sort="Kamat, Sandhya K" uniqKey="Kamat S" first="Sandhya K" last="Kamat">Sandhya K. Kamat</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology & Therapeutics, Seth Gordhandas Sunderdas Medical College & King Edwards Medical Hospital, Mumbai, Maharashtra, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology & Therapeutics, Seth Gordhandas Sunderdas Medical College & King Edwards Medical Hospital, Mumbai, Maharashtra</wicri:regionArea><wicri:noRegion>Maharashtra</wicri:noRegion></affiliation></author><author><name sortKey="Chandy, Sujith J" sort="Chandy, Sujith J" uniqKey="Chandy S" first="Sujith J" last="Chandy">Sujith J. Chandy</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology & Clinical Pharmacology, Christian Medical College, Vellore, Tamil Nadu, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology & Clinical Pharmacology, Christian Medical College, Vellore, Tamil Nadu</wicri:regionArea><wicri:noRegion>Tamil Nadu</wicri:noRegion></affiliation></author><author><name sortKey="Medhi, Bikash" sort="Medhi, Bikash" uniqKey="Medhi B" first="Bikash" last="Medhi">Bikash Medhi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology, Postgraduate Institute of Medical Education & Research, Chandigarh</wicri:regionArea><wicri:noRegion>Chandigarh</wicri:noRegion></affiliation></author><author><name sortKey="Tripathi, Raakhi K" sort="Tripathi, Raakhi K" uniqKey="Tripathi R" first="Raakhi K" last="Tripathi">Raakhi K. Tripathi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology & Therapeutics, Seth Gordhandas Sunderdas Medical College & King Edwards Medical Hospital, Mumbai, Maharashtra, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology & Therapeutics, Seth Gordhandas Sunderdas Medical College & King Edwards Medical Hospital, Mumbai, Maharashtra</wicri:regionArea><wicri:noRegion>Maharashtra</wicri:noRegion></affiliation></author><author><name sortKey="Shetty, Yashashri C" sort="Shetty, Yashashri C" uniqKey="Shetty Y" first="Yashashri C" last="Shetty">Yashashri C. Shetty</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology & Therapeutics, Seth Gordhandas Sunderdas Medical College & King Edwards Medical Hospital, Mumbai, Maharashtra, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology & Therapeutics, Seth Gordhandas Sunderdas Medical College & King Edwards Medical Hospital, Mumbai, Maharashtra</wicri:regionArea><wicri:noRegion>Maharashtra</wicri:noRegion></affiliation></author><author><name sortKey="Raj, John Michael" sort="Raj, John Michael" uniqKey="Raj J" first="John Michael" last="Raj">John Michael Raj</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biostatistics, St. John's Medical College, Bengaluru, Karnataka, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Biostatistics, St. John's Medical College, Bengaluru, Karnataka</wicri:regionArea><wicri:noRegion>Karnataka</wicri:noRegion></affiliation></author><author><name sortKey="Kaushal, Sandeep" sort="Kaushal, Sandeep" uniqKey="Kaushal S" first="Sandeep" last="Kaushal">Sandeep Kaushal</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, Dayanand Medical College & Hospital, Ludhiana, Punjab, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology, Dayanand Medical College & Hospital, Ludhiana, Punjab</wicri:regionArea><wicri:noRegion>Punjab</wicri:noRegion></affiliation></author><author><name sortKey="Balakrishnan, S" sort="Balakrishnan, S" uniqKey="Balakrishnan S" first="S" last="Balakrishnan">S. Balakrishnan</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh</wicri:regionArea><wicri:noRegion>Madhya Pradesh</wicri:noRegion></affiliation></author><author><name sortKey="Atal, Shubham" sort="Atal, Shubham" uniqKey="Atal S" first="Shubham" last="Atal">Shubham Atal</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh</wicri:regionArea><wicri:noRegion>Madhya Pradesh</wicri:noRegion></affiliation></author><author><name sortKey="Tripathi, Santanu K" sort="Tripathi, Santanu K" uniqKey="Tripathi S" first="Santanu K" last="Tripathi">Santanu K. Tripathi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical & Experimental Pharmacology, School of Tropical Medicine, Kolkata, West Bengal, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Clinical & Experimental Pharmacology, School of Tropical Medicine, Kolkata, West Bengal</wicri:regionArea><wicri:noRegion>West Bengal</wicri:noRegion></affiliation></author><author><name sortKey="Badyal, Dinesh K" sort="Badyal, Dinesh K" uniqKey="Badyal D" first="Dinesh K" last="Badyal">Dinesh K. Badyal</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, Christian Medical College, Ludhiana, Punjab, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology, Christian Medical College, Ludhiana, Punjab</wicri:regionArea><wicri:noRegion>Punjab</wicri:noRegion></affiliation></author><author><name sortKey="Dikshit, Harihar" sort="Dikshit, Harihar" uniqKey="Dikshit H" first="Harihar" last="Dikshit">Harihar Dikshit</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, Indira Gandhi Institute of Medical Science, Patna, Bihar, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology, Indira Gandhi Institute of Medical Science, Patna, Bihar</wicri:regionArea><wicri:noRegion>Bihar</wicri:noRegion></affiliation></author><author><name sortKey="Roy, Sukalyan Saha" sort="Roy, Sukalyan Saha" uniqKey="Roy S" first="Sukalyan Saha" last="Roy">Sukalyan Saha Roy</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, Indira Gandhi Institute of Medical Science, Patna, Bihar, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology, Indira Gandhi Institute of Medical Science, Patna, Bihar</wicri:regionArea><wicri:noRegion>Bihar</wicri:noRegion></affiliation></author><author><name sortKey="Trivedi, Niyati" sort="Trivedi, Niyati" uniqKey="Trivedi N" first="Niyati" last="Trivedi">Niyati Trivedi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, Medical College Baroda, Vadodara, Ahmedabad, Gujarat, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology, Medical College Baroda, Vadodara, Ahmedabad, Gujarat</wicri:regionArea><wicri:noRegion>Gujarat</wicri:noRegion></affiliation></author><author><name sortKey="Chatterjee, Suparna" sort="Chatterjee, Suparna" uniqKey="Chatterjee S" first="Suparna" last="Chatterjee">Suparna Chatterjee</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, Institute of Postgraduate Medical Education & Research, Kolkata, West Bengal, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology, Institute of Postgraduate Medical Education & Research, Kolkata, West Bengal</wicri:regionArea><wicri:noRegion>West Bengal</wicri:noRegion></affiliation></author><author><name sortKey="Desai, Chetna" sort="Desai, Chetna" uniqKey="Desai C" first="Chetna" last="Desai">Chetna Desai</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, B.J. Medical College, Ahmedabad, Gujarat, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology, B.J. Medical College, Ahmedabad, Gujarat</wicri:regionArea><wicri:noRegion>Gujarat</wicri:noRegion></affiliation></author><author><name sortKey="Tripathi, C D" sort="Tripathi, C D" uniqKey="Tripathi C" first="C D" last="Tripathi">C D Tripathi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, Vardhman Mahavir Medical College & Safdarjung Hospital, New Delhi, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology, Vardhman Mahavir Medical College & Safdarjung Hospital, New Delhi</wicri:regionArea><wicri:noRegion>New Delhi</wicri:noRegion></affiliation></author><author><name sortKey="Rege, Nirmala N" sort="Rege, Nirmala N" uniqKey="Rege N" first="Nirmala N" last="Rege">Nirmala N. Rege</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology & Therapeutics, Seth Gordhandas Sunderdas Medical College & King Edwards Medical Hospital, Mumbai, Maharashtra, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology & Therapeutics, Seth Gordhandas Sunderdas Medical College & King Edwards Medical Hospital, Mumbai, Maharashtra</wicri:regionArea><wicri:noRegion>Maharashtra</wicri:noRegion></affiliation></author><author><name sortKey="Gupta, Pooja" sort="Gupta, Pooja" uniqKey="Gupta P" first="Pooja" last="Gupta">Pooja Gupta</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, All India Institute of Medical Sciences, New Delhi, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology, All India Institute of Medical Sciences, New Delhi</wicri:regionArea><wicri:noRegion>New Delhi</wicri:noRegion></affiliation></author><author><name sortKey="Raveendran, R" sort="Raveendran, R" uniqKey="Raveendran R" first="R" last="Raveendran">R. Raveendran</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, Jawaharlal Institute of Postgraduate Education & Research, Puducherry, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Pharmacology, Jawaharlal Institute of Postgraduate Education & Research, Puducherry</wicri:regionArea><wicri:noRegion>Puducherry</wicri:noRegion></affiliation></author><author><name sortKey="Kaul, Rajni" sort="Kaul, Rajni" uniqKey="Kaul R" first="Rajni" last="Kaul">Rajni Kaul</name><affiliation wicri:level="1"><nlm:affiliation>Division of Basic Medical Sciences, New Delhi, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Division of Basic Medical Sciences, New Delhi</wicri:regionArea><wicri:noRegion>New Delhi</wicri:noRegion></affiliation></author><author><name sortKey="Kshirsagar, Nilima A" sort="Kshirsagar, Nilima A" uniqKey="Kshirsagar N" first="Nilima A" last="Kshirsagar">Nilima A. Kshirsagar</name><affiliation wicri:level="1"><nlm:affiliation>National Chair Clinical Pharmacology, Indian Council for Medical Research, New Delhi, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>National Chair Clinical Pharmacology, Indian Council for Medical Research, New Delhi</wicri:regionArea><wicri:noRegion>New Delhi</wicri:noRegion></affiliation></author></analytic><series><title level="j">The Indian journal of medical research</title><idno type="ISSN">0971-5916</idno></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>COVID-19 (drug therapy)</term><term>COVID-19 (prevention & control)</term><term>Cross-Sectional Studies (MeSH)</term><term>Female (MeSH)</term><term>Health Personnel (MeSH)</term><term>Humans (MeSH)</term><term>Hydroxychloroquine (adverse effects)</term><term>Hydroxychloroquine (therapeutic use)</term><term>Male (MeSH)</term><term>Pre-Exposure Prophylaxis (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Femelle (MeSH)</term><term>Humains (MeSH)</term><term>Hydroxychloroquine (effets indésirables)</term><term>Hydroxychloroquine (usage thérapeutique)</term><term>Mâle (MeSH)</term><term>Personnel de santé (MeSH)</term><term>Prophylaxie pré-exposition (MeSH)</term><term>Études transversales (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Hydroxychloroquine</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>COVID-19</term></keywords><keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Hydroxychloroquine</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>COVID-19</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Hydroxychloroquine</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Hydroxychloroquine</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Cross-Sectional Studies</term><term>Female</term><term>Health Personnel</term><term>Humans</term><term>Male</term><term>Pre-Exposure Prophylaxis</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Femelle</term><term>Humains</term><term>Mâle</term><term>Personnel de santé</term><term>Prophylaxie pré-exposition</term><term>Études transversales</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>Background & objectives</b></p><p>Hydroxychloroquine (HCQ), reported to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication in in vitro studies, has been recommended for prophylaxis of COVID-19 in healthcare workers (HCWs). The objective of this study was to assess short-term adverse events (AEs) of HCQ in HCWs.</p></div><div type="abstract" xml:lang="en"><p><b>Methods</b></p><p>This cross-sectional study among consenting HCWs taking prophylaxis and working in hospitals with COVID-19 patients used online forms to collect details of HCWs, comorbidities, prophylactic drugs used and AEs after the first dose of HCQ. Verification of dose and AEs was done by personal contact. Multivariate logistic regression analysis was done to determine the effect of age, gender and dose of HCQ on AE.</p></div><div type="abstract" xml:lang="en"><p><b>Results</b></p><p>Of the 1303 HCWs included, 98.4 per cent (n=1282) took HCQ and 66 per cent (n=861) took 800 mg as first day's dose. Among the 19.9 per cent (n=259) reporting AEs, 1.5 per cent (n=20) took treatment for AE, none were hospitalized and three discontinued HCQ. Gastrointestinal AEs were the most common (172, 13.2%), with less in older [odds ratio (OR) 0.56, 95% confidence interval (CI) 0.35-0.89], with more in females (OR 2.46, 95% CI 1.78-3.38) and in those taking a total dose of 800 mg on day one compared to a lower dose. Hypoglycaemia (1.1%, n=14), cardiovascular events (0.7%, n=9) and other AEs were minimal.</p></div><div type="abstract" xml:lang="en"><p><b>Interpretation & conclusions</b></p><p>HCQ prophylaxis first dose was well tolerated among HCWs as evidenced by a low discontinuation. For adverse effects, a small number required treatment, and none required hospitalization. The study had limitations of convenience sampling and lack of laboratory and electrocardiography confirmation of AEs.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" IndexingMethod="Curated" Owner="NLM"><PMID Version="1">33818480</PMID><DateCompleted><Year>2021</Year><Month>04</Month><Day>15</Day></DateCompleted><DateRevised><Year>2021</Year><Month>04</Month><Day>15</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0971-5916</ISSN><JournalIssue CitedMedium="Internet"><Volume>153</Volume><Issue>1 & 2</Issue><PubDate><MedlineDate>2021 Jan & Feb</MedlineDate></PubDate></JournalIssue><Title>The Indian journal of medical research</Title><ISOAbbreviation>Indian J Med Res</ISOAbbreviation></Journal><ArticleTitle>Safety of hydroxychloroquine in healthcare workers for COVID-19 prophylaxis.</ArticleTitle><Pagination><MedlinePgn>219-226</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.4103/ijmr.IJMR_2294_20</ELocationID><Abstract><AbstractText Label="Background & objectives" NlmCategory="UNASSIGNED">Hydroxychloroquine (HCQ), reported to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication in in vitro studies, has been recommended for prophylaxis of COVID-19 in healthcare workers (HCWs). The objective of this study was to assess short-term adverse events (AEs) of HCQ in HCWs.</AbstractText><AbstractText Label="Methods" NlmCategory="UNASSIGNED">This cross-sectional study among consenting HCWs taking prophylaxis and working in hospitals with COVID-19 patients used online forms to collect details of HCWs, comorbidities, prophylactic drugs used and AEs after the first dose of HCQ. Verification of dose and AEs was done by personal contact. Multivariate logistic regression analysis was done to determine the effect of age, gender and dose of HCQ on AE.</AbstractText><AbstractText Label="Results" NlmCategory="UNASSIGNED">Of the 1303 HCWs included, 98.4 per cent (n=1282) took HCQ and 66 per cent (n=861) took 800 mg as first day's dose. Among the 19.9 per cent (n=259) reporting AEs, 1.5 per cent (n=20) took treatment for AE, none were hospitalized and three discontinued HCQ. Gastrointestinal AEs were the most common (172, 13.2%), with less in older [odds ratio (OR) 0.56, 95% confidence interval (CI) 0.35-0.89], with more in females (OR 2.46, 95% CI 1.78-3.38) and in those taking a total dose of 800 mg on day one compared to a lower dose. Hypoglycaemia (1.1%, n=14), cardiovascular events (0.7%, n=9) and other AEs were minimal.</AbstractText><AbstractText Label="Interpretation & conclusions" NlmCategory="UNASSIGNED">HCQ prophylaxis first dose was well tolerated among HCWs as evidenced by a low discontinuation. For adverse effects, a small number required treatment, and none required hospitalization. The study had limitations of convenience sampling and lack of laboratory and electrocardiography confirmation of AEs.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Faruqui</LastName><ForeName>Atiya R</ForeName><Initials>AR</Initials><AffiliationInfo><Affiliation>Department of Pharmacology, St. John's Medical College, Bengaluru, Karnataka, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Xavier</LastName><ForeName>Denis</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Department of Pharmacology, St. John's Medical College, Bengaluru, Karnataka, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kamat</LastName><ForeName>Sandhya K</ForeName><Initials>SK</Initials><AffiliationInfo><Affiliation>Department of Pharmacology & Therapeutics, Seth Gordhandas Sunderdas Medical College & King Edwards Medical Hospital, Mumbai, Maharashtra, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chandy</LastName><ForeName>Sujith J</ForeName><Initials>SJ</Initials><AffiliationInfo><Affiliation>Department of Pharmacology & Clinical Pharmacology, Christian Medical College, Vellore, Tamil Nadu, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Medhi</LastName><ForeName>Bikash</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Department of Pharmacology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tripathi</LastName><ForeName>Raakhi K</ForeName><Initials>RK</Initials><AffiliationInfo><Affiliation>Department of Pharmacology & Therapeutics, Seth Gordhandas Sunderdas Medical College & King Edwards Medical Hospital, Mumbai, Maharashtra, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Shetty</LastName><ForeName>Yashashri C</ForeName><Initials>YC</Initials><AffiliationInfo><Affiliation>Department of Pharmacology & Therapeutics, Seth Gordhandas Sunderdas Medical College & King Edwards Medical Hospital, Mumbai, Maharashtra, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Raj</LastName><ForeName>John Michael</ForeName><Initials>JM</Initials><AffiliationInfo><Affiliation>Department of Biostatistics, St. John's Medical College, Bengaluru, Karnataka, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kaushal</LastName><ForeName>Sandeep</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Pharmacology, Dayanand Medical College & Hospital, Ludhiana, Punjab, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Balakrishnan</LastName><ForeName>S</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Pharmacology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Atal</LastName><ForeName>Shubham</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Pharmacology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tripathi</LastName><ForeName>Santanu K</ForeName><Initials>SK</Initials><AffiliationInfo><Affiliation>Department of Clinical & Experimental Pharmacology, School of Tropical Medicine, Kolkata, West Bengal, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Badyal</LastName><ForeName>Dinesh K</ForeName><Initials>DK</Initials><AffiliationInfo><Affiliation>Department of Pharmacology, Christian Medical College, Ludhiana, Punjab, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dikshit</LastName><ForeName>Harihar</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Department of Pharmacology, Indira Gandhi Institute of Medical Science, Patna, Bihar, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Roy</LastName><ForeName>Sukalyan Saha</ForeName><Initials>SS</Initials><AffiliationInfo><Affiliation>Department of Pharmacology, Indira Gandhi Institute of Medical Science, Patna, Bihar, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Trivedi</LastName><ForeName>Niyati</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Department of Pharmacology, Medical College Baroda, Vadodara, Ahmedabad, Gujarat, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chatterjee</LastName><ForeName>Suparna</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Pharmacology, Institute of Postgraduate Medical Education & Research, Kolkata, West Bengal, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Desai</LastName><ForeName>Chetna</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of Pharmacology, B.J. Medical College, Ahmedabad, Gujarat, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tripathi</LastName><ForeName>C D</ForeName><Initials>CD</Initials><AffiliationInfo><Affiliation>Department of Pharmacology, Vardhman Mahavir Medical College & Safdarjung Hospital, New Delhi, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rege</LastName><ForeName>Nirmala N</ForeName><Initials>NN</Initials><AffiliationInfo><Affiliation>Department of Pharmacology & Therapeutics, Seth Gordhandas Sunderdas Medical College & King Edwards Medical Hospital, Mumbai, Maharashtra, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gupta</LastName><ForeName>Pooja</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Pharmacology, All India Institute of Medical Sciences, New Delhi, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Raveendran</LastName><ForeName>R</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Department of Pharmacology, Jawaharlal Institute of Postgraduate Education & Research, Puducherry, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kaul</LastName><ForeName>Rajni</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Division of Basic Medical Sciences, New Delhi, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kshirsagar</LastName><ForeName>Nilima A</ForeName><Initials>NA</Initials><AffiliationInfo><Affiliation>National Chair Clinical Pharmacology, Indian Council for Medical Research, New Delhi, India.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>India</Country><MedlineTA>Indian J Med Res</MedlineTA><NlmUniqueID>0374701</NlmUniqueID><ISSNLinking>0971-5916</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>4QWG6N8QKH</RegistryNumber><NameOfSubstance UI="D006886">Hydroxychloroquine</NameOfSubstance></Chemical></ChemicalList><SupplMeshList><SupplMeshName Type="Protocol" UI="C000705127">COVID-19 drug treatment</SupplMeshName></SupplMeshList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000086382" MajorTopicYN="N">COVID-19</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName><QualifierName UI="Q000517" MajorTopicYN="Y">prevention & control</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003430" MajorTopicYN="N">Cross-Sectional Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006282" MajorTopicYN="Y">Health Personnel</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006886" MajorTopicYN="Y">Hydroxychloroquine</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="N">adverse effects</QualifierName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D065129" MajorTopicYN="N">Pre-Exposure Prophylaxis</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Adverse events</Keyword><Keyword MajorTopicYN="N">COVID-19</Keyword><Keyword MajorTopicYN="N">chloroquine</Keyword><Keyword MajorTopicYN="N">coronavirus</Keyword><Keyword MajorTopicYN="N">healthcare workers</Keyword><Keyword MajorTopicYN="N">hydroxychloroquine</Keyword><Keyword MajorTopicYN="N">prophylaxis</Keyword><Keyword MajorTopicYN="N">rational</Keyword></KeywordList><CoiStatement>None</CoiStatement></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2021</Year><Month>4</Month><Day>5</Day><Hour>12</Hour><Minute>36</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2021</Year><Month>4</Month><Day>6</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2021</Year><Month>4</Month><Day>16</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">33818480</ArticleId><ArticleId IdType="pii">IndianJMedRes_2021_153_1_219_311938</ArticleId><ArticleId IdType="doi">10.4103/ijmr.IJMR_2294_20</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Inde</li></country></list><tree><country name="Inde"><noRegion><name sortKey="Faruqui, Atiya R" sort="Faruqui, Atiya R" uniqKey="Faruqui A" first="Atiya R" last="Faruqui">Atiya R. Faruqui</name></noRegion><name sortKey="Atal, Shubham" sort="Atal, Shubham" uniqKey="Atal S" first="Shubham" last="Atal">Shubham Atal</name><name sortKey="Badyal, Dinesh K" sort="Badyal, Dinesh K" uniqKey="Badyal D" first="Dinesh K" last="Badyal">Dinesh K. Badyal</name><name sortKey="Balakrishnan, S" sort="Balakrishnan, S" uniqKey="Balakrishnan S" first="S" last="Balakrishnan">S. Balakrishnan</name><name sortKey="Chandy, Sujith J" sort="Chandy, Sujith J" uniqKey="Chandy S" first="Sujith J" last="Chandy">Sujith J. Chandy</name><name sortKey="Chatterjee, Suparna" sort="Chatterjee, Suparna" uniqKey="Chatterjee S" first="Suparna" last="Chatterjee">Suparna Chatterjee</name><name sortKey="Desai, Chetna" sort="Desai, Chetna" uniqKey="Desai C" first="Chetna" last="Desai">Chetna Desai</name><name sortKey="Dikshit, Harihar" sort="Dikshit, Harihar" uniqKey="Dikshit H" first="Harihar" last="Dikshit">Harihar Dikshit</name><name sortKey="Gupta, Pooja" sort="Gupta, Pooja" uniqKey="Gupta P" first="Pooja" last="Gupta">Pooja Gupta</name><name sortKey="Kamat, Sandhya K" sort="Kamat, Sandhya K" uniqKey="Kamat S" first="Sandhya K" last="Kamat">Sandhya K. Kamat</name><name sortKey="Kaul, Rajni" sort="Kaul, Rajni" uniqKey="Kaul R" first="Rajni" last="Kaul">Rajni Kaul</name><name sortKey="Kaushal, Sandeep" sort="Kaushal, Sandeep" uniqKey="Kaushal S" first="Sandeep" last="Kaushal">Sandeep Kaushal</name><name sortKey="Kshirsagar, Nilima A" sort="Kshirsagar, Nilima A" uniqKey="Kshirsagar N" first="Nilima A" last="Kshirsagar">Nilima A. Kshirsagar</name><name sortKey="Medhi, Bikash" sort="Medhi, Bikash" uniqKey="Medhi B" first="Bikash" last="Medhi">Bikash Medhi</name><name sortKey="Raj, John Michael" sort="Raj, John Michael" uniqKey="Raj J" first="John Michael" last="Raj">John Michael Raj</name><name sortKey="Raveendran, R" sort="Raveendran, R" uniqKey="Raveendran R" first="R" last="Raveendran">R. Raveendran</name><name sortKey="Rege, Nirmala N" sort="Rege, Nirmala N" uniqKey="Rege N" first="Nirmala N" last="Rege">Nirmala N. Rege</name><name sortKey="Roy, Sukalyan Saha" sort="Roy, Sukalyan Saha" uniqKey="Roy S" first="Sukalyan Saha" last="Roy">Sukalyan Saha Roy</name><name sortKey="Shetty, Yashashri C" sort="Shetty, Yashashri C" uniqKey="Shetty Y" first="Yashashri C" last="Shetty">Yashashri C. Shetty</name><name sortKey="Tripathi, C D" sort="Tripathi, C D" uniqKey="Tripathi C" first="C D" last="Tripathi">C D Tripathi</name><name sortKey="Tripathi, Raakhi K" sort="Tripathi, Raakhi K" uniqKey="Tripathi R" first="Raakhi K" last="Tripathi">Raakhi K. Tripathi</name><name sortKey="Tripathi, Santanu K" sort="Tripathi, Santanu K" uniqKey="Tripathi S" first="Santanu K" last="Tripathi">Santanu K. Tripathi</name><name sortKey="Trivedi, Niyati" sort="Trivedi, Niyati" uniqKey="Trivedi N" first="Niyati" last="Trivedi">Niyati Trivedi</name><name sortKey="Xavier, Denis" sort="Xavier, Denis" uniqKey="Xavier D" first="Denis" last="Xavier">Denis Xavier</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:33818480" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a CovidChloroV1
| This area was generated with Dilib version V0.6.38. |  |